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Lifestyle and genetic determinants of folate and vitamin B12 levels in a general adult population

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Reduced secretion of gastric acid and pepsin, from the use of H 2 blocker or proton-pump inhibitor (PPI) drugs, can reduce the absorption of protein-bound (dietary) vitamin B 12 , although not of supplemental vitamin B 12

In kidney aging studies, it protected renal tubular epithelial cells, reduced renal inflammation, and improved renal function

For example, pregnant women might need more folate, while older adults might need more calcium and vitamin D