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Unlike insulin, which is essential for managing blood glucose levels but often associated with weight gain due to its role in glucose storage, Ozempic focuses directly on appetite suppression and fat reduction

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10.1021/acschemneuro.3c00168 308 MandalP

For doses above 0.8 mg, it also led to a weight loss of up to 4.8 kg (compared to a 1.2 kg reduction with a placebo)