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Alternative pharmacotherapy may be appropriate for some patients

doi: 10.1038/nri.2016.112 528 ChangPPBarralPFitchJPratamaAMaCSKalliesAet al

Unlike older compounds in the same class, it has relatively little activity on: Cortisol secretion Prolactin secretion Appetite stimulation This selectivity is one reason it remains popular in peptide protocols

Do I need to follow a specific diet while taking tirzepatide Tirzepatide naturally reduces appetite, which typically leads to lower caloric intake without the need for extreme dietary restriction

It is well-established that disruption of the hepatic fatty acid oxidation, lipogenesis, and insulin signaling pathways contributes to hepatic steatosis