Contraindications GLP-1s arent recommended for those with a history of thyroid carcinoma, pancreatitis, some endocrine conditions, and GI motility disorders
Companies compete primarily on large-scale peptide synthesis capabilities, manufacturing capacity, regulatory compliance, supply reliability, and expertise in complex peptide production
Generic oral B12 is inexpensive (often just a few dollars/month)
Ecotoxicol Environ Saf 284:116854 Sonnweber T, Nachbaur D, Schroll A, Nairz M, Seifert M, Demetz E, Haschka D et al (2014) Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB
Due to this, doctors avoid giving GLP-1 drugs to anyone with either a personal or family history of MTC or multiple endocrine neoplasia syndrome type 2