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The starting dose of Mounjaro is 2.5mg, and if appropriate, youll move up to 5mg after 4 weeks

Glucose-lowering and insulin-sensitizing actions of exendin-4: studies in obese diabetic (ob/ob, db/db) mice, diabetic fatty Zucker rats, and diabetic rhesus monkeys (Macaca mulatta)

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Additionally, GLP-1 receptor activation by GLP-1RAs can mimic effects on these cells similar to those on pancreatic beta cells, suggesting that this pathway also modulates neural insulin production [44]