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PubMed laboratory research record [PMID: 39216884] PubMed record related to this compound for laboratory literature review

This maintenance period was followed by a 5-week follow up period

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No research program is without constraints, and acknowledging these limitations helps set appropriate expectations

The aim of this study is to exploit GSH-responsive AP site capture reagent (AP probe-net), which responses to the elevated glutathione (GSH) levels in the tumor micro-environment (TME), releasing reactive alkoxyamine to trap AP sites and block the APE1-mediated BER for targeted anti-tumor activity against ATC