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The most specific antibodies are directed at the amidated C-terminus of GLP-1

Because animal studies cannot entirely predict outcomes in humans, these findings do not automatically mean the same effects would happen in human pregnancies

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Early GLP-1 development efforts were hindered by rapid degradation by dipeptidyl peptidase-4, short duration of action, and gastrointestinal intolerance at supraphysiologic exposure levels

This reduction results in lighter and even skin tone