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The construct incorporates an N-terminal nona-D-arginine (D-Arg)9 cell-penetrating tag fused to a segment derived from the FOXO4-p53 interaction domain, giving the peptide a strongly cationic overall character driven by its multiple arginine and lysine residues, along with a single tryptophan that supports UV monitoring at 280 nm during analytical workflows

After allowing a 24 h period for attachment, GSH-depleted cells were treated with 5 or 10 mol/ml ASA for 48 h and NAC in some cases as described above

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A Holistic, Lifestyle-Integrated Approach Peptide therapy should never be used in isolation

51 NovinscakT.BrcicL.StaresinicM.JukicI.RadicB.PevecD.et al (2008)