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The authors describe the high clinical benefit rate in their cohort as a clarion call for rigorous, systematic investigation, but thus far there has been no large-scale or prospective, controlled investigation for MCAS

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Complex Patient Journeys Reveal Both Promise and Pitfalls Beyond Weight Loss That "miracle weight loss shot" flooding your social media

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Serious but rare risks include pancreatitis, gallbladder problems, and, in people with a personal or family history of certain thyroid conditions, a theoretical risk of thyroid tumours (seen in animal studies)

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In the study, US researchers from Mass General Brigham, a nonprofit network of doctors and hospitals headquartered in Boston, analysed real-world data from more than 90,000 heart failure patients who were obese and had type 2 diabetes

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