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In addition, it is not recommended if you have acute pancreatitis, severe allergic reaction to GLP-1 drugs, are pregnant, or have gastroparesis and inflammatory bowel disease
These two also have a sparing effect upon each other
Stomach acid destroys them before they reach your bloodstream
In addition, in contrast with previous findings, a systematic review and metanalysis by Overbeek et al
![Tirzepatide vs. Semaglutide: Which GLP-1 Better Preserves Muscle? [SURMOUNT-5 Data]](https://www.clinicalnutritioncenter.com/wp-content/uploads/2026/04/research-image-2026-04-10.jpg)
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