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For example, limitations in BBB penetration efficiency allow for limited distribution in the CNS, which may affect efficacy

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However, Koska et al

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Beyond initial approvals, several other factors will shape long-term access

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Earlier studies showed a weight-recovery curve that was almost exponential in shape, with rapid weight regain early on, followed by a shallower slope that reached a new steady state over time

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GLP-1 receptor agonists have gained attention for weight management during perimenopause, a metabolically complex transition affecting women typically in their 40s and early 50s

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