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For context, the concentrations required to activate intracellular cascades such as PI3K/Akt, upregulate BDNF, or stimulate autophagy in neuronal tissue are derived from preclinical studies that used substantially higher relative exposures than those achievable in the human brain at therapeutic doses
The research is pretty compelling
Curr Opin Otolaryngol Head Neck Surg 2015;23:209-15
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If nausea remains intolerable, pre-dose with 15-20g protein 30 minutes before injection to buffer the gastric effect
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