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What solvent should be used to reconstitute GHK-Cu

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Five studies of BPC-157 reviewed by the FDA were of short duration, had small sample sizes and evaluated doses that were likely exploratory in nature, an agency reviewer said

This profile is consistent with the function of copper as a SOD cofactor and with the observed modulation of antioxidant defense genes Profile observed in models (synthesis): Activity at the level of fibroblasts and extracellular matrix cells stimulation of the synthesis of structural proteins Copper transport function coupled with the activity of Cu-dependent enzymes Modulation of repair and antioxidant gene expression in transcriptomic studies Pro-angiogenic and pro-regenerative profile in wound healing models In research models, GHK-Cu is interpreted as bifunctional extracellular matrix modulator a signal stimulating the synthesis of connective tissue components and a carrier providing copper as a cofactor for enzymes responsible for the maturation and cross-linking of this matrix

For topical-only GHK-Cu users on metformin, this monitoring protocol is not necessary