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A recent proteomic study suggested altered mitochondrial function in the cerebrovasculature isolated from deceased cognitively healthy E4 carriers compared to non-E4 carriers, indicating that cerebrovascular bioenergetics may indeed be altered in cognitively healthy E4 carriers (Ojo et al., 2021)
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The IV (intravenous) method of administration allows much higher doses of glutathione to enter the cells than would otherwise be possible by dietary modification or oral supplements
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