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SmPCs for Wegovy and Saxenda are available on the EMC

However, FOXO4-DRI treatment significantly reduced the expression of these detrimental SASP factors and, critically, restored the proliferation of GC-1 spg cells in the co-culture system, as evidenced by CCK-8 assays and PCNA expression, without inducing apoptosis in the spermatogonia

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But the preclinical data, combined with growing clinical observations, suggests these compounds may support disc healing through mechanisms that conventional treatments simply do not address