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387 The literature on topiroxostat reports certain adverse effects, including polyarthritis, nasopharyngitis, and an increase in liver enzymes

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The most common reasons: using a standard (non-effervescent, non-liposomal) capsule with poor gut absorption, inconsistent daily use, expecting visible results before the typical 8-12 week window, unrealistic expectations set by marketing claims, low supporting nutrients like Vitamin C, or continued sun exposure without adequate sunscreen, which counteracts skin brightening effects