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B12s role in maintaining healthy circadian rhythms may help prevent the sleep disturbances and daytime fatigue commonly experienced with SAD

14 JonitzA.LochnerK.TischerT.HansmannD.BaderR

Further studies involving robust mechanistic validation, pharmacokinetic profiling, and clinical translation are essential to determine whether these compounds possess genuine therapeutic potential or if their effects are limited to experimental settings

early orthopedic reviews note promise but emphasize the need for rigorous human trials