While we quantified cellular aggregation, a second phenotype, harder to characterize at short time scales, is YcgR dependent regulation of flagella based swimming 25,26,27
Various studies have been performed recently too, such as this one by the US National Library of Medicine, but there is no conclusive evidence of it working for skin lightening yet
This method is often preferred by those looking for maximum impact with lower, more targeted doses
CORRECTING GLUTATHIONE DEFICIENCY AND MITOCHONDRIAL DYSFUNCTION IN OLDER HUMANS: A RANDOMIZED CLINICAL TRIAL Efficacy of glutathione for the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, multicenter, pilot study, Effect of Glutathione Infusion on Leg Arterial Circulation, Cutaneous Microcirculation, and Pain-Free Walking Distance in Patients With Peripheral Obstructive Arterial Disease: A Randomized, Double-Blind, Placebo-Controlled Trial
The picture is mixed and no large trial has been done, so it is promising rather than proven