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The polymorphism in GSTM1 and GSTT1 genes, leads to complete lack of activity of their corresponding enzymes and is responsible for poor elimination of carcinogenic substances which are potential sources of reactive oxygen species (Rebbeck, 1997

Additionally, disc degeneration in OTLFK patients was associated with abnormal sagittal spinal parameters and endplate injury

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Once depleted, energy is drawn from fatty acids