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The RMSD plot of the fusion proteins complex with HSA demonstrates that all three systems reached a stable state after 50 ns of the MD simulation
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Long-term treatment must be considered in addition to short-term medicines, taking into account the potential consequences of the artificial tears, anti-inflammatory eye drops, and punctal plugs are examples of conventional treatments for dry eye disease that can be successful, but long-term use can be costly and may result in adverse effects that limit patient adherence [38, 39]
But outside of trials, this guidance often falls through the cracks
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