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Yes, when taken at recommended doses

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For in vitro cytotoxicity assays where benzyl alcohol vehicle effects could confound results, include matched Bacteriostatic Water vehicle controls at the same final benzyl alcohol concentration as the peptide treatment to distinguish compound-specific from vehicle-associated biological effects

Inhibition of SREBP transcriptional activity by a boron-containing compound improves lipid homeostasis in diet-induced obesity

Participants were given one of three doses of retatrutide, or a placebo (a dummy injection), and followed for 80 weeks (around 18 months)