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International Journal of Molecular Sciences, 24 (3), 2959
Much of the reported 40% lean mass loss with GLP-1 use is coming from the liver," explained exercise physiologist Keith Baar, a professor of Neurobiology, Physiology and Behavior and Physiology and Membrane Biology
One of the challenges with GLP-1 therapy is that protein requirements dont fall just because appetite does
Exacerbation of acetaminophen-induced disturbances of liver sinusoidal endothelial cells in the absence of Kupffer cells in mice
A post-mortem study of human pancreases demonstrated proliferative effects in those cases with GLP-1RA use, which were manifest by an increased mass of the pancreas along with increased frequency of PanIN1 and PanIN2 lesions compared to diabetes controls 23
