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A recent small pilot study using the same calorie-restricted diet with a macronutrient composition identical to that of the Zone diet resulted in complete disease remission in all six diabetic patients within 6 months (7)
Never skip doses or try to make up for missed injections by taking extra medication
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Measurement of undercarboxylated osteocalcin is technically challenging, with inter-assay variability and confounding by vitamin K status complicating interpretation
Together, they are commonly studied for their combined influence on appetite-related pathways, energy intake signaling, and metabolic regulation markers
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