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Thereafter, throughout the 40-week extension, HbA1c was stable during DPP-4 inhibition, whereas in placebo-treated patients, HbA1c increased throughout the study period, resulting in a difference in HbA1c between the groups after 52 weeks of 1.1% (11 mmol/mol) [Figure 5
Lancet 2 , 359362 (1973)
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156,164 Additionally, ATP stimulates liver sinusoidal endothelial cells (LSECs) to express HGF and IL-6 in response to hepatocyte damage, promoting regenerative processes
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