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Efficacy and safety outcomes for originator TNF inhibitors and biosimilars in rheumatoid arthritis and psoriasis trials: a systematic literature review

However, when very high oral doses are taken, approximately 1% can be absorbed through passive diffusion, independent of intrinsic factor, which explains how mega-doses can still raise serum levels

Novel delivery systems: Explore novel delivery systems such as liposomes and nanoparticles to enhance the retention time of polypeptides in the skin and improve their therapeutic effects