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The effect of the NK2 tachykinin receptor antagonist SR 48968 (saredutant) on neurokinin A-induced bronchoconstriction in asthmatics
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Bub A, et al
Two Previous studies [1, 25] addressing NAC use were limited to only modest doses of NAC (6001200 mg/day) and short duration of treatment (8 weeks) and showed a 32% significant improvement in glutathione peroxidase levels and a 6% improvement in pain score, with a recommendation of the use of higher doses of NAC for longer duration
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