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Secondary endpoints were safety, side effects, and efficacy
Periventricular leukomalacia Periventricular leukomalacia (PVL) is a diffuse damage of the cerebral white matter that extends beyond the periventricular regions found predominantly in preterm infants
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In addition, quinolinic acid stimulates synaptosomal glutamate release by acting as an NMDA receptor agonist and, in astrocytes, decreases the expression of glutamate transporters and increases their release, thereby increasing extracellular glutamate levels [367, 368]
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