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Due to lack of data on safety in pregnant humans, women who are pregnant or planning to become pregnant should not take a GLP-1 agonist
FDA staff's own briefing document, posted publicly ahead of the meeting as part of the docket, proposes that TB-500 (free base) and TB-500 acetate not be added to the list, citing incomplete physicochemical characterization, a lack of evidence of effectiveness for wound healing (including an in-vitro fibroblast study in which TB-500 reportedly did not induce wound healing), and insufficient nonclinical and clinical safety data
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Novo Nordisk then used the Semaglutide formula to create an FDA-approved weight loss drug called Wegovy
Though hens are not vegetarians, they are sometimes fed a vegetarian diet, which indicates their feed contains no animal byproducts
