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While a temporary decrease in NCOA4 results in less breakdown of ferritin, leading to increased iron storage and therefore less available iron in the cell [41], long-term reduction in NCOA4 expression or function, as observed in animal studies, leads to an overload of iron and oxidative stress [42]
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Ahmed MS, Langer H, Abed M, Voelkl J, Lang F
Diets were administered for 3 days prior to procedures and maintained post-operatively
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