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Following rigorous quality control measures, which included the exclusion of duplicate entries, reports with incomplete demographic data (age or gender), and cases with missing temporal information, we retained 13,047 AE reports associated with concomitant GLP-1 receptor agonist and metformin therapy for final analysis

The cytokines IL-6 and TNF, as well the prostaglandin PGE 2 , are capable of stimulating aromatase activity

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The dose-response relationship of paracetamol and liver injury is in contrast to so-called idiosyncratic drug-induced liver injury, which is restricted to a subset of susceptible individuals

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