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2009;21(6):609-e22

Retatrutide Titration Schedule: Standard Phase 2 Protocol The table below reflects the Phase 2 trial protocol for the primary escalation arm (Jastreboff et al., NEJM 2023)

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This approach may provide an attractive alternative to directly target the desired oncogene (or protein of another pathogenic activity), focusing instead on developing tools to target the zDHHCs controlling the proper (or pathological) localization of the protein