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Although data from early phase trials suggest that retatrutide is well tolerated with a similar adverse event profile to GLP-1 RAs, additional research assessing long-term safety and efficacy of retatrutide in people living with obesity and/or T2D (including cardiovascular outcomes) is awaited over the next five years

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At 300 pounds, the difference between semaglutide (approximately 45 pounds) and retatrutide (approximately 86 pounds) is 41 pounds

For people who wake up ravenous or need to get out the door quickly, that 60-90 minute wait can feel like an eternity