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The review warns that since VEGF/VEGFR2 pathways are active in roughly half of human cancers (from ovarian to melanoma)
Both classes of Grxs share a similar basic structure and possess all the necessary motifs required to interact with GSH moieties in a highly similar manner [41]
Nature 505, 559563
Work in the lab of PS has been supported by Canada Research Chairs, Canada Foundation for Innovation, Alberta Prion Research Institute, Alberta InnovatesNovartis, MS Society of Canada, National MS Society, National Institutes of Health, Canadian Institutes for Health Research, the Hopewell M.I.N.D prize, Alzheimers Society, Barford Foundation, Krembil Foundation, and generous philanthropists
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