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Furthermore, animal research has found that extremely high doses of alpha-lipoic acid may promote oxidation, alter liver enzymes, and place strain on liver and breast tissue (38, To date, very few studies have looked at the safety of alpha-lipoic acid in children and pregnant women
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By modulating 2-AR signaling in MDSCs, there is potential to overcome the immune suppression that hinders the effectiveness of other cancer immunotherapies [119]
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