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Gene therapy studies using HGF have demonstrated beneficial effects in animal models of amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and cerebral ischemia, with HGF treatment promoting neurite extension, increasing synaptogenesis, and enhancing functional recovery
Compared with injection, intranasal delivery is favorably recognized as a less invasive method of bypassing the blood-brain barrier [10, 13, 23]
BPC-157 remains investigational with limited human clinical data
TB-500 reconstitutes well in sterile bacteriostatic water or sterile saline
Diabetologia 54 , 965978 (2011)
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