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We circumvented the need for CYP-mediated bioactivation of AQ and DEAQ by exposing the cells to the synthetic AQ-QI and DEAQ-QI, the reactive metabolites of AQ

The study looked back on their health records for up to three years, beginning when they started taking either a GLP-1 receptor agonist most commonly semaglutide, liraglutide or dulaglutide or another type of medication, called an SGLT2 inhibitor, to treat their diabetes

This usually means the person has a body mass index (BMI) of 30 or higher

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