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Prior to the age of Ozempic, many of the trendiest diet aids were supplements, not prescription medications: green tea extract, caffeine pills, ephedra
Lancet Diabetes & Endocrinology, 13(3), 188-197
Comparison with atorvastatin binding to HMG-CoA reductase, its intended target, offers clues on how to modify the statin to reduce RyR1 binding, while leaving binding to HMG-CoA reductase unperturbed
However, clinical data specifically evaluating their concurrent use are lacking, so theoretical considerations and individual patient factors must guide decision-making with healthcare provider input
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