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Covalent binding NAPQI is believed to exert its toxic effects by binding covalently to liver proteins leading to protein denaturation and necrosis of liver cells[6, 26, 27]
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PMID 19459860
Esters should be diluted in aqueous solution immediately before use
This substantial rise in NO levels under SMG conditions likely reflects aberrant activation of NOS (e.g., iNOS) and indicates heightened oxidative stress and inflammation
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