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Adults with an overweight BMI of 27 kg/m 2 or greater with at least one weight-related health condition, such as high blood pressure, high blood sugar, or high cholesterol

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For instance, the viral delivery of glial cell line-derived neurotrophic factor (GDNF) to the striatum in conjunction with homotopic transplantation of human iPSC-derived midbrain DA neurons, improved brain-wide mDA target innervation and functional recovery compared to graft-only controls