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Avoid skipping meals or extending fasts beyond 12 hours during your first month on semaglutide, as prolonged fasting combined with appetite suppression can trigger both metabolic headaches and migraine episodes

DOI 10.1016/j.tibs.2011.07.001

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Current evidence from large-scale clinical trials and regulatory surveillance does not establish a causal link between GLP-1 receptor agonists and increased risk of venous thromboembolism (deep vein thrombosis or pulmonary embolism)

Davis M et al