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While the exact reasons arent clear, researchers point to things like body weight, side effect sensitivity, and hormonal factors
Cyanocobalamin is more common and has a shorter body retention
Interestingly, the analogue 23 with six consecutive ureido residues proved to be efficient despite its 7% potency compared to GLP-1-G 2 ( 1 )
In some cases, the patient requires a more potent dose after this adjustment
doi: 10.1097/JGP.0b013e31822001c1 22 CabouC.BurcelinR
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