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EMA and the European medicines regulatory network hold regular meetings with the marketing authorisation holders (MAHs) to gain a full oversight of the market situation, including current and anticipated shortages, and closely monitor the effects of any mitigation actions
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This is a condition where blood flow to the optic nerve is suddenly reduced or cut off, causing permanent vision loss
Similarly, fibrin, fibrinogen, collagen and other blood-derived molecules, together with DAMPs released from dying cells signal to neuroglia and instigate reactive gliosis
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