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How Hydroquinone Disrupts Melanin Production at the Enzyme Level Hydroquinone (1,4-dihydroxybenzene) is a phenolic compound that penetrates the stratum corneum and diffuses into melanocytes, where it binds covalently to tyrosinase and oxidises the enzyme's copper-containing active site

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However, rare yet serious conditions such as endophthalmitis, secondary cataracts, and retinal detachment can also arise [81]

E., Kawarai T., Sato C., Salehi-Rad S., Fisman G

Ignoring other antioxidants: Glutathione works best when combined with supporting nutrients like vitamin C and selenium