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Alpha Lipoic Acid : This is another potent antioxidant that helps neutralize free radicals and reduce oxidative stress
In sum, a host of pharmacologic agents from novel small molecules to repurposed anesthetic drugs are being utilized to stabilize mitochondria, reduce DAMPs release, and optimize immune cell metabolism during the perioperative period
Additionally, IS promotes the generation of red blood cell (RBC)-derived microparticles (MPs)
Neurosci Biobehav Rev 114:134155 Zhang L, Huang J, Zhang Z, Cao Z (2021) Altered metabolites in the occipital lobe in migraine without aura during the attack and the interictal period
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