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IV dose of valproic acid to rats circles: Bile intact rats triangles: Bile exteriorized rats Valproic acid glucuronide Smith, Phase II Metabolism, UNC Chapel Hill, 8/2012 e.g

Pigment cell research, 14(3), 155-160

Don't double up on doses to "catch up." If you frequently find yourself missing doses, it might be worth discussing with your healthcare provider whether your current schedule is realistic or if adjustments would be helpful