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N., & Ryals, R
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Published in the New England Journal of Medicine, this trial enrolled 2,539 adults with obesity or overweight (with at least one weight-related comorbidity) who did not have diabetes
Oxidative stress is a well-established driver of neuronal injury in diabetic encephalopathy, as chronic hyperglycemia elevates reactive oxygen species, disrupts mitochondrial function, and accelerates lipid peroxidation 26,27
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