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Other situations requiring prompt medical contact include signs of allergic reactions (difficulty breathing, swelling of the face or throat, severe rash)call 911 for severe allergic reactionssymptoms of thyroid tumors (a lump or swelling in the neck, hoarseness, difficulty swallowing), or signs of kidney problems (decreased urination, swelling in legs or feet, unusual fatigue)

Agents in this group include peroxisome proliferator-activated receptor agonists (e.g., pioglitazone, elafibranor, saroglitazar), bile acid-farnesoid X receptor axis regulators (obeticholic acid), de novo lipogenesis inhibitors (aramchol, NDI-010976), and fibroblast growth factor 21/19 analogs

It is building the tolerability foundation for sustainable escalation

Reduced caloric intake associated with Mounjaro's appetite-suppressing effects may also contribute to feelings of light-headedness, especially during the initial weeks of treatment