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Toxicology 228 , 98108 (2006)

Clinical data from STEP and SURMOUNT trials show tirzepatide users achieved approximately 20-22% weight loss at highest doses, compared to semaglutide's 15-17% at comparable timepoints

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Retatrutide long-term side effects Because retatrutide is still in the trial phase, and the studies have been relatively short (up to a year long), we dont know what the long-term side effects will be