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Beyond the stimulation of hepatic glucose production, it also affects hepatic fat metabolism promoting lipid oxidation and lowering lipid synthesis

Preclinical and clinical data suggest that FXR and PPAR dual modulators can improve insulin sensitivity, reduce hepatic steatosis, and attenuate fibrosis, which may complement the actions of GLP-1/GIP/GCG receptors agonists

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Apr 2015;66(4):304-318

When theres less saliva flowing through the mouth, this encourages bacteria that contribute to bad breath and the formation of cavities to thrive