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If there is no irritation, itching, or redness, the product is safe to use
More clinical evidence can be found on the role of GLP1R agonists such as exenatide can improve vascular endothelial dysfunction in diabetic patients, as has been found in this clinical trial by Hu et al., results suggested that exenatide improved the endothelial dysfunction reflected by digital reactive hyperemia index in newly diagnosed patients with T2DM, and the effect was not inferior to single metformin [59]
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Off-Label Use: A Growing Concern GLP-1s approved for T2D are frequently used off-label for weight loss, raising concerns among both employers and health plans
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